Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3fzn D7K Benzoylformate decarboxylase 4.1.1.7

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3fzn D7KBenzoylformate decarboxylase 4.1.1.7 1.465
3fsj D7KBenzoylformate decarboxylase 4.1.1.7 1.204
4jub TPPBenzoylformate decarboxylase 4.1.1.7 1.179
4juf TPPBenzoylformate decarboxylase 4.1.1.7 1.171
4k9n TZDBenzoylformate decarboxylase 4.1.1.7 1.146
4k9p TPPBenzoylformate decarboxylase 4.1.1.7 1.145
1po7 TZDBenzoylformate decarboxylase 4.1.1.7 1.140
4k9o TPPBenzoylformate decarboxylase 4.1.1.7 1.125
4mpr TPPBenzoylformate decarboxylase 4.1.1.7 1.117
4ju8 TZDBenzoylformate decarboxylase 4.1.1.7 1.106
4mq5 TPPBenzoylformate decarboxylase 4.1.1.7 1.106
5dgt TZDBenzoylformate decarboxylase 4.1.1.7 1.106
4ju9 TZDBenzoylformate decarboxylase 4.1.1.7 1.105
4qel TZDBenzoylformate decarboxylase 4.1.1.7 1.103
1bfd TPPBenzoylformate decarboxylase 4.1.1.7 1.094
2v3w TPPBenzoylformate decarboxylase 4.1.1.7 1.090
4mpp TZDBenzoylformate decarboxylase 4.1.1.7 1.085
4juc TPPBenzoylformate decarboxylase 4.1.1.7 1.074
1mcz TDPBenzoylformate decarboxylase 4.1.1.7 1.065
4mzx TZDBenzoylformate decarboxylase 4.1.1.7 1.054
2fwn TDPBenzoylformate decarboxylase 4.1.1.7 1.052
4gg1 TZDBenzoylformate decarboxylase 4.1.1.7 1.010
4jd5 TZDBenzoylformate decarboxylase 4.1.1.7 1.007
4gm0 TZDBenzoylformate decarboxylase 4.1.1.7 0.985
4gm1 TZDBenzoylformate decarboxylase 4.1.1.7 0.980
4gm4 TZDBenzoylformate decarboxylase 4.1.1.7 0.959
4cok TPPPyruvate decarboxylase / 0.904
2vk8 TPPPyruvate decarboxylase isozyme 1 / 0.891
2w93 TPPPyruvate decarboxylase isozyme 1 / 0.890
1pox TPPPyruvate oxidase 1.2.3.3 0.866
2q5o TPWIndole-3-pyruvate decarboxylase 4.1.1.74 0.852
5eja TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.848
1y9d TPPPyruvate oxidase 1.2.3.3 0.839
5esd TDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.827
5eso TDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.818
5ej9 TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.817
2qta TDPPyruvate dehydrogenase E1 component 1.2.4.1 0.815
5c4i TPPOxalate oxidoreductase subunit alpha / 0.815
5c4i TPPOxalate oxidoreductase subunit beta / 0.815
2pan TDPGlyoxylate carboligase 4.1.1.47 0.808
5ej6 TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.807
3lq2 TDPPyruvate dehydrogenase E1 component 1.2.4.1 0.801
2vk4 TPPPyruvate decarboxylase 4.1.1.1 0.800
2x7j TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.799
5ej7 TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.799
2q5q TPWIndole-3-pyruvate decarboxylase 4.1.1.74 0.796
1pvd TPPPyruvate decarboxylase isozyme 1 / 0.792
5ej5 TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.788
2uza HTLPyruvate synthase / 0.787
2c3y HTLPyruvate synthase / 0.785
4zp1 TPPPyruvate decarboxylase 4.1.1.1 0.782
1pyd TDPPyruvate decarboxylase isozyme 1 / 0.779
1jsc TPPAcetolactate synthase catalytic subunit, mitochondrial 2.2.1.6 0.778
1w88 TDPPyruvate dehydrogenase E1 component subunit alpha 1.2.4.1 0.770
1w88 TDPPyruvate dehydrogenase E1 component subunit beta 1.2.4.1 0.770
3hwx TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.770
5ej8 TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.768
3lq4 TDPPyruvate dehydrogenase E1 component 1.2.4.1 0.767
2jla TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.762
5ej4 TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.762
2ez9 TDKPyruvate oxidase 1.2.3.3 0.757
1l8a TDPPyruvate dehydrogenase E1 component 1.2.4.1 0.752
1umc TDP2-oxoisovalerate dehydrogenase subunit alpha 1.2.4.4 0.749
1umc TDP2-oxoisovalerate dehydrogenase subunit beta 1.2.4.4 0.749
3iae D7KBenzaldehyde lyase / 0.749
2jlc TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.746
2j9f THV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1.2.4.4 0.745
2j9f THV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 1.2.4.4 0.745
2g25 TDKPyruvate dehydrogenase E1 component 1.2.4.1 0.743
2g28 TDKPyruvate dehydrogenase E1 component 1.2.4.1 0.743
3d7k D7KBenzaldehyde lyase / 0.740
1ovm TPPIndole-3-pyruvate decarboxylase 4.1.1.74 0.739
2qtc TDKPyruvate dehydrogenase E1 component 1.2.4.1 0.736
3dv0 TPWPyruvate dehydrogenase E1 component subunit alpha 1.2.4.1 0.734
3dv0 TPWPyruvate dehydrogenase E1 component subunit beta 1.2.4.1 0.734
1itz TPPTransketolase, chloroplastic 2.2.1.1 0.732
1pow TPPPyruvate oxidase 1.2.3.3 0.732
1rp7 TZDPyruvate dehydrogenase E1 component 1.2.4.1 0.729
2ji7 OXTOxalyl-CoA decarboxylase 4.1.1.8 0.728
1v11 TDP2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1.2.4.4 0.726
1kek HTLPyruvate synthase / 0.724
5exd TPPOxalate oxidoreductase subunit alpha / 0.722
5exd TPPOxalate oxidoreductase subunit beta / 0.722
2r8o T5XTransketolase 1 / 0.721
1ols TDP2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1.2.4.4 0.716
3zhq TPPMultifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.716
1gpu THDTransketolase 1 2.2.1.1 0.715
1ni4 TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 1.2.4.1 0.715
1ni4 TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial 1.2.4.1 0.715
3ey9 TDPPyruvate dehydrogenase [ubiquinone] 1.2.5.1 0.713
2c31 TZDOxalyl-CoA decarboxylase 4.1.1.8 0.710
2uz1 TPPBenzaldehyde lyase / 0.708
2iea TDPPyruvate dehydrogenase E1 component 1.2.4.1 0.707
3eya TDPPyruvate dehydrogenase [ubiquinone] 1.2.5.1 0.707
3oe1 TDLPyruvate decarboxylase 4.1.1.1 0.707
5ahk TPPAcetolactate synthase II, large subunit / 0.707
3zhs TD6Multifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.702
2r5n TPPTransketolase 1 / 0.699
1trk TPPTransketolase 1 2.2.1.1 0.696
3m7i TPPTransketolase / 0.696
3upt TPPTransketolase / 0.695
4c7x TPPTransketolase / 0.694
3m34 TPPTransketolase / 0.692
1ozh HE3Acetolactate synthase, catabolic 2.2.1.6 0.689
2ag0 TPPBenzaldehyde lyase / 0.689
3zhu TD8Multifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.689
1ay0 TPPTransketolase 1 2.2.1.1 0.687
2c42 TPPPyruvate synthase / 0.686
1ngs TPPTransketolase 1 2.2.1.1 0.684
3zhr TPPMultifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.684
1tkc M6TTransketolase 1 2.2.1.1 0.683
3ahj TPPProbable phosphoketolase / 0.683
3duf R1TPyruvate dehydrogenase E1 component subunit alpha 1.2.4.1 0.682
3duf R1TPyruvate dehydrogenase E1 component subunit beta 1.2.4.1 0.682
1tkb N1TTransketolase 1 2.2.1.1 0.681
3exh TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 1.2.4.1 0.680
3exh TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial 1.2.4.1 0.680
2c3o TPPPyruvate synthase / 0.679
3zhv TDWMultifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.678
4qpz TPPBenzaldehyde lyase / 0.674
3dva TPWPyruvate dehydrogenase E1 component subunit alpha 1.2.4.1 0.671
3dva TPWPyruvate dehydrogenase E1 component subunit beta 1.2.4.1 0.671
3zht TD9Multifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.671
3ahe THDProbable phosphoketolase / 0.669
3exf TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 1.2.4.1 0.669
3exf TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial 1.2.4.1 0.669
2ezt TDMPyruvate oxidase 1.2.3.3 0.665
2pda TPPPyruvate synthase / 0.663
3iaf TPPBenzaldehyde lyase / 0.663
3ahi HTLProbable phosphoketolase / 0.657
2olr ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.655
2ag1 TPPBenzaldehyde lyase / 0.653
2c3u 2TPPyruvate synthase / 0.653
1ky2 GNPGTP-binding protein YPT7 / 0.651