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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3fko FKO Mitogen-activated protein kinase 14

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3fko FKOMitogen-activated protein kinase 14 / 1.040
3fkn FKNMitogen-activated protein kinase 14 / 0.851
3fi4 FI4Mitogen-activated protein kinase 14 / 0.823
2b1p AIZMitogen-activated protein kinase 10 2.7.11.24 0.772
3fl4 FL4Mitogen-activated protein kinase 14 / 0.768
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
3iw7 IPKMitogen-activated protein kinase 14 / 0.728
3que 3FFMitogen-activated protein kinase 14 / 0.724
3fly FLYMitogen-activated protein kinase 14 / 0.706
1wbw LI4Mitogen-activated protein kinase 14 / 0.677
4ag8 AXIVascular endothelial growth factor receptor 2 2.7.10.1 0.675
3l8x N4DMitogen-activated protein kinase 14 / 0.673
1zzl TZYMitogen-activated protein kinase 14 / 0.672
4e5f 0N7Polymerase acidic protein / 0.660
1pmv 537Mitogen-activated protein kinase 10 2.7.11.24 0.659
4eh6 0ONMitogen-activated protein kinase 14 / 0.659
3hp5 52PMitogen-activated protein kinase 14 / 0.657
4c58 824Cyclin-G-associated kinase 2.7.11.1 0.656
3ha8 5JZMitogen-activated protein kinase 14 / 0.655
3fi3 JK2Mitogen-activated protein kinase 10 2.7.11.24 0.653