Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3cjg KIM Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3cjg KIMVascular endothelial growth factor receptor 2 2.7.10.1 0.988
2hzi JINTyrosine-protein kinase ABL1 2.7.10.2 0.762
1m52 P17Tyrosine-protein kinase ABL1 2.7.10.2 0.736
4bbf O19Tyrosine-protein kinase JAK2 / 0.726
3sw4 18KCyclin-dependent kinase 2 2.7.11.22 0.722
4fko 20KCyclin-dependent kinase 2 2.7.11.22 0.719
4dea NHIAurora kinase A 2.7.11.1 0.714
4aot GW8Serine/threonine-protein kinase 10 2.7.11.1 0.705
1pxm CK5Cyclin-dependent kinase 2 2.7.11.22 0.704
3sw7 19KCyclin-dependent kinase 2 2.7.11.22 0.704
2xir 00JVascular endothelial growth factor receptor 2 2.7.10.1 0.697
2c5n CK8Cyclin-dependent kinase 2 2.7.11.22 0.690
2vgp AD6Aurora kinase B-A 2.7.11.1 0.683
3cjf SAVVascular endothelial growth factor receptor 2 2.7.10.1 0.683
2p2h 994Vascular endothelial growth factor receptor 2 2.7.10.1 0.682
3uo5 0BXAurora kinase A 2.7.11.1 0.681
3tki S25Serine/threonine-protein kinase Chk1 2.7.11.1 0.678
3ezv EZVCyclin-dependent kinase 2 2.7.11.22 0.676
1z5m LI83-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.674
1urw I1PCyclin-dependent kinase 2 2.7.11.22 0.672
2xck MH43-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.670
3unj 0BXCyclin-dependent kinase 2 2.7.11.22 0.667
4c3f 7KWTyrosine-protein kinase Lck 2.7.10.2 0.667
2wxv WXVCyclin-dependent kinase 2 2.7.11.22 0.664
2x1n X1NCyclin-dependent kinase 2 2.7.11.22 0.664
1oir HDYCyclin-dependent kinase 2 2.7.11.22 0.663
3cgo JNOMitogen-activated protein kinase 10 2.7.11.24 0.661
3vo3 0KFVascular endothelial growth factor receptor 2 2.7.10.1 0.660
4a4o 664Serine/threonine-protein kinase PLK1 2.7.11.21 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4eqc XR1Serine/threonine-protein kinase PAK 1 2.7.11.1 0.658
4eut BX7Serine/threonine-protein kinase TBK1 2.7.11.1 0.658
4d58 BI9Focal adhesion kinase 1 2.7.10.2 0.655
2xmy CDKCyclin-dependent kinase 2 2.7.11.22 0.653
3ztx ZTXAurora kinase B-A 2.7.11.1 0.653
2jkk BI9Focal adhesion kinase 1 2.7.10.2 0.652
1oec AA2Fibroblast growth factor receptor 2 / 0.651
4l7f 1V5Mitogen-activated protein kinase 8 2.7.11.24 0.651
2p33 J07Mitogen-activated protein kinase 10 2.7.11.24 0.650