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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2zvb SAH Precorrin-3 C17-methyltransferase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
2zvb SAHPrecorrin-3 C17-methyltransferase / 1.051
2zvc SAHPrecorrin-3 C17-methyltransferase / 1.008
2qbu SAHPrecorrin-2 methyltransferase / 0.897
3nut SAHPrecorrin-3 methylase / 0.817
2ybo SAHMethyltransferase / 0.816
3nd1 SAHPrecorrin-6A synthase (Deacetylating) / 0.814
1v9a SAHUncharacterized protein / 0.801
3ndc SAHPrecorrin-4 C(11)-methyltransferase 2.1.1.133 0.800
2npn SAMPutative cobalamin synthesis related protein / 0.798
1s4d SAHUroporphyrinogen-III C-methyltransferase 2.1.1.107 0.786
2e0n SAHPrecorrin-2 C20-methyltransferase / 0.720
1cbf SAHCobalt-precorrin-4 C(11)-methyltransferase 2.1.1.271 0.717
2ek3 SAHDiphthine synthase / 0.701
2dv7 SAHDiphthine synthase / 0.698
4x3l MTARNA 2'-O ribose methyltransferase / 0.695
2bb3 SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE) / 0.690
2e15 SAHDiphthine synthase / 0.685
2ed5 SAHDiphthine synthase / 0.683
2egv SAMRibosomal RNA small subunit methyltransferase E 2.1.1.193 0.683
4pzk SAHPutative tRNA (cytidine(34)-2'-O)-methyltransferase / 0.682
2e17 SAHDiphthine synthase / 0.680
2eni SAHDiphthine synthase / 0.677
2p6l SAHDiphthine synthase / 0.677
2egl SAHDiphthine synthase / 0.673
2dxv SAHDiphthine synthase / 0.672
2e16 SAHDiphthine synthase / 0.672
2dxx SAHDiphthine synthase / 0.671
2ek7 SAHDiphthine synthase / 0.670
2dv5 SAHDiphthine synthase / 0.669
2ha8 SAHProbable methyltransferase TARBP1 / 0.669
2p6i SAHDiphthine synthase / 0.669
4jl8 ADPAdenylate kinase / 0.669
4cnf MTASpoU rRNA methylase / 0.668
2pck SAHDiphthine synthase / 0.667
2dxw SAHDiphthine synthase / 0.665
2eh2 SAHDiphthine synthase / 0.665
3nk7 SAM23S rRNA (adenosine(1067)-2'-O)-methyltransferase / 0.665
4kgn SAHtRNA (cytidine(34)-2'-O)-methyltransferase / 0.665
4cng SAHSpoU rRNA methylase / 0.664
5a7y SAHtRNA (adenine(9)-N1)-methyltransferase 2.1.1.218 0.663
2e07 SAHDiphthine synthase / 0.662
1mjh ATPUniversal stress protein MJ0577 / 0.661
2ele SAHDiphthine synthase / 0.661
2p9d SAHDiphthine synthase / 0.661
2pcm SAHDiphthine synthase / 0.661
2yy8 MTAtRNA (cytidine(56)-2'-O)-methyltransferase / 0.661
2owk SAHDiphthine synthase / 0.658
2dsg SAHDiphthine synthase / 0.656
2egb SAHDiphthine synthase / 0.656
2p5c SAHDiphthine synthase / 0.655
2ehl SAHDiphthine synthase / 0.654
2z6r SAHDiphthine synthase / 0.654
1mxi SAHtRNA (cytidine(34)-2'-O)-methyltransferase / 0.653
2ed3 SAHDiphthine synthase / 0.652
2p6k SAHDiphthine synthase / 0.651