Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2zdy ADP [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2zdy ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.927
2zkj ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.777
3a0t ADPSensor histidine kinase / 0.767
3d2r ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.740
1jm6 ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.738
1gjv AGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 2.7.11.4 0.736
1thn ADPAnti-sigma F factor / 0.704
1mx0 ANPType 2 DNA topoisomerase 6 subunit B / 0.699
1z5c ADPType 2 DNA topoisomerase 6 subunit B / 0.699
2c2a ADPSensor histidine kinase / 0.694
1z5a ADPType 2 DNA topoisomerase 6 subunit B / 0.689
4prx ADPDNA gyrase subunit B / 0.683
4bix ADPSensor histidine kinase CpxA / 0.679
2bu8 ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.678
3crl ANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.669
3sl2 ATPSensor histidine kinase WalK / 0.669
1nhh ANPDNA mismatch repair protein MutL / 0.666
2bu2 ATP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.662
1pvg ANPDNA topoisomerase 2 5.99.1.3 0.661
4gt8 ADPSensor protein VraS 2.7.13.3 0.661
1i59 ANPChemotaxis protein CheA 2.7.13.3 0.659
2e0a ANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.658
1id0 ANPSensor protein PhoQ 2.7.13.3 0.657
1kp2 ATPArgininosuccinate synthase 6.3.4.5 0.656
4biw ANPSensor histidine kinase CpxA / 0.655
2b9j ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.653
4oa9 ANPProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.652
5il1 SAMN6-adenosine-methyltransferase 70 kDa subunit / 0.652