Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2w1h L0F Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2w1h L0FCyclin-dependent kinase 2 2.7.11.22 0.829
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
3s0o 50ZCyclin-dependent kinase 2 2.7.11.22 0.678
3vf9 477Tyrosine-protein kinase SYK 2.7.10.2 0.671
3vf8 0JETyrosine-protein kinase SYK 2.7.10.2 0.662
2w1g L0GAurora kinase A 2.7.11.1 0.661
4e5f 0N7Polymerase acidic protein / 0.660
3r8v Z62Cyclin-dependent kinase 2 2.7.11.22 0.657
2vto LZ8Cyclin-dependent kinase 2 2.7.11.22 0.651
3rni 21ZCyclin-dependent kinase 2 2.7.11.22 0.651
4aua 4AUCyclin-dependent kinase 6 2.7.11.22 0.651