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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2viv VG2 Urokinase-type plasminogen activator 3.4.21.73

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2viv VG2Urokinase-type plasminogen activator 3.4.21.73 0.873
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
1owd 497Urokinase-type plasminogen activator 3.4.21.73 0.721
1owe 675Urokinase-type plasminogen activator 3.4.21.73 0.716
4fue 7UPUrokinase-type plasminogen activator 3.4.21.73 0.693
4fuj 1U9Urokinase-type plasminogen activator 3.4.21.73 0.676
1sqt UI3Urokinase-type plasminogen activator 3.4.21.73 0.660
1owk 303Urokinase-type plasminogen activator 3.4.21.73 0.658
3v0x ANHCationic trypsin 3.4.21.4 0.658