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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2pmi AGS Cyclin-dependent protein kinase PHO85 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2pmi AGSCyclin-dependent protein kinase PHO85 2.7.11.22 0.837
4b8l A0PAurora kinase B-A 2.7.11.1 0.676
5l8k ADPAurora kinase A 2.7.11.1 0.668
1zp9 ATPRIO-type serine/threonine-protein kinase Rio1 2.7.11.1 0.656
1c3x 8IGPurine nucleoside phosphorylase 2.4.2.1 0.655