Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2p1o NLA Protein TRANSPORT INHIBITOR RESPONSE 1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2p1o NLAProtein TRANSPORT INHIBITOR RESPONSE 1 / 0.969
2p1p IACProtein TRANSPORT INHIBITOR RESPONSE 1 / 0.800
2eg8 FOTDihydroorotase 3.5.2.3 0.682
4iwn GEKCarboxy-S-adenosyl-L-methionine synthase / 0.679
2prh 238Dihydroorotate dehydrogenase (quinone), mitochondrial 1.3.5.2 0.671
2tpl HPPTyrosine phenol-lyase 4.1.99.2 0.671
4ie0 PD2Alpha-ketoglutarate-dependent dioxygenase FTO / 0.669
4i13 FOLDihydrofolate reductase 1.5.1.3 0.667
4cd2 FOLDihydrofolate reductase 1.5.1.3 0.665
2pja 33ZCarboxypeptidase B / 0.663
3o5t ADPNitrogen regulatory protein P-II 1 / 0.657
3t0i SAHPutative methyltransferase / 0.657
4azw SAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD / 0.654
1dhf FOLDihydrofolate reductase 1.5.1.3 0.653
3qe2 NAPNADPH--cytochrome P450 reductase / 0.653
1u5a BIKL-lactate dehydrogenase 1.1.1.27 0.652
4yao 2AMNADPH--cytochrome P450 reductase / 0.650