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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2o0u C0M Mitogen-activated protein kinase 10 2.7.11.24

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2o0u C0MMitogen-activated protein kinase 10 2.7.11.24 1.054
1efz PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.744
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
1m3q ANGN-glycosylase/DNA lyase 3.2.2 0.744
2o2u 738Mitogen-activated protein kinase 10 2.7.11.24 0.729
3fi3 JK2Mitogen-activated protein kinase 10 2.7.11.24 0.713
3p5k P5KMitogen-activated protein kinase 14 / 0.663
3q9z TXQCasein kinase II subunit alpha 2.7.11.1 0.662
1ozq PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1p0e PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1ulb GUNPurine nucleoside phosphorylase 2.4.2.1 0.660
3bld PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4gcx PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4h7z GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hvx QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
3erk SB4Mitogen-activated protein kinase 1 2.7.11.24 0.659
4ftn 2HKSerine/threonine-protein kinase Chk1 2.7.11.1 0.656
3iw5 DF3Mitogen-activated protein kinase 14 / 0.654
3p7b P7BMitogen-activated protein kinase 14 / 0.653
3roc 29AMitogen-activated protein kinase 14 / 0.650