Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2nvc ITA Aldose reductase 1.1.1.21

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2nvc ITAAldose reductase 1.1.1.21 0.865
2hv5 ZSTAldose reductase 1.1.1.21 0.710
2duz ZSTAldose reductase 1.1.1.21 0.708
1t40 ID5Aldose reductase 1.1.1.21 0.703
2iqd LPAAldose reductase 1.1.1.21 0.694
2ikj 393Aldose reductase 1.1.1.21 0.692
2pdi ZSTAldose reductase 1.1.1.21 0.692
2dux ZSTAldose reductase 1.1.1.21 0.691
3ght LDTAldose reductase 1.1.1.21 0.691
3ghu LDTAldose reductase 1.1.1.21 0.690
3lbo LDTAldose reductase 1.1.1.21 0.690
3m4h 388Aldose reductase 1.1.1.21 0.690
2pdf ZSTAldose reductase 1.1.1.21 0.689
1z3n 3NAAldose reductase 1.1.1.21 0.687
2inz OHPAldose reductase 1.1.1.21 0.686
3t42 3T4Aldose reductase 1.1.1.21 0.685
2pzn 393Aldose reductase 1.1.1.21 0.678
3s3g TLTAldose reductase 1.1.1.21 0.677
2pd5 ZSTAldose reductase 1.1.1.21 0.676
2ikh LITAldose reductase 1.1.1.21 0.675
2pdx ZSTAldose reductase 1.1.1.21 0.675
3m64 393Aldose reductase 1.1.1.21 0.675
2pdg 47DAldose reductase 1.1.1.21 0.674
3ghs LDTAldose reductase 1.1.1.21 0.674
1frb ZSTAldose reductase-related protein 2 / 0.673
2i17 LDTAldose reductase 1.1.1.21 0.673
2qxw LDTAldose reductase 1.1.1.21 0.673
3ghr LDTAldose reductase 1.1.1.21 0.673
1us0 LDTAldose reductase 1.1.1.21 0.672
2i16 LDTAldose reductase 1.1.1.21 0.672
2is7 2CLAldose reductase 1.1.1.21 0.672
3mc5 393Aldose reductase 1.1.1.21 0.672
3ld5 LDTAldose reductase 1.1.1.21 0.668
2ipw 2CLAldose reductase 1.1.1.21 0.667
2pdp 393Aldose reductase 1.1.1.21 0.667
2pdl TOLAldose reductase 1.1.1.21 0.662
1zua TOLAldo-keto reductase family 1 member B10 1.1.1 0.661
3lql LDTAldose reductase 1.1.1.21 0.654
3lz5 LDTAldose reductase 1.1.1.21 0.654