Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2iqd LPA Aldose reductase 1.1.1.21

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2iqd LPAAldose reductase 1.1.1.21 0.809
2inz OHPAldose reductase 1.1.1.21 0.716
2pdc 393Aldose reductase 1.1.1.21 0.708
3s3g TLTAldose reductase 1.1.1.21 0.696
2nvc ITAAldose reductase 1.1.1.21 0.694
3ght LDTAldose reductase 1.1.1.21 0.689
2is7 2CLAldose reductase 1.1.1.21 0.688
2ikj 393Aldose reductase 1.1.1.21 0.686
3ghu LDTAldose reductase 1.1.1.21 0.686
3t42 3T4Aldose reductase 1.1.1.21 0.686
3lbo LDTAldose reductase 1.1.1.21 0.685
2pdx ZSTAldose reductase 1.1.1.21 0.681
3ld5 LDTAldose reductase 1.1.1.21 0.679
3ghs LDTAldose reductase 1.1.1.21 0.669
3lz5 LDTAldose reductase 1.1.1.21 0.669
2i17 LDTAldose reductase 1.1.1.21 0.668
2qxw LDTAldose reductase 1.1.1.21 0.668
3ghr LDTAldose reductase 1.1.1.21 0.668
1us0 LDTAldose reductase 1.1.1.21 0.667
2i16 LDTAldose reductase 1.1.1.21 0.667
2pdq 47DAldose reductase 1.1.1.21 0.653
2ipw 2CLAldose reductase 1.1.1.21 0.652