Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2fsn ADP Archaeal actin homolog

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2fsn ADPArchaeal actin homolog / 1.044
4ehu ANP2-hydroxyisocaproyl-CoA dehydratase activator / 0.798
4eht ADP2-hydroxyisocaproyl-CoA dehydratase activator / 0.770
2zgy GDPPlasmid segregation protein ParM / 0.768
2v51 ATPActin, alpha skeletal muscle / 0.754
4a62 ANPPlasmid segregation protein ParM / 0.750
3eks ATPActin-5C / 0.744
2p9k ATPActin-related protein 2 / 0.739
3m6g ATPActin, alpha skeletal muscle / 0.733
4b1v ATPActin, alpha skeletal muscle / 0.728
1wua ATPActin, alpha skeletal muscle / 0.720
4cbx ATPActin-2 / 0.718
4pkg ATPActin, alpha skeletal muscle / 0.718
3mn7 ATPActin-5C / 0.717
4pki ATPActin, alpha skeletal muscle / 0.716
2q97 ATPActin, alpha skeletal muscle / 0.714
3a5m ATPMajor actin / 0.708
3dnt ATPSerine/threonine-protein kinase toxin HipA / 0.706
2zgz GNPPlasmid segregation protein ParM / 0.702
4a61 ANPPlasmid segregation protein ParM / 0.699
3w3d ATPActin, gamma-enteric smooth muscle / 0.698
3daw ATPActin, alpha skeletal muscle / 0.696
3mn9 ATPActin-5C / 0.696
4jhd ANPActin-5C / 0.696
3a5o ATPMajor actin / 0.694
3eku ATPActin-5C / 0.694
4pl8 ATPActin, alpha skeletal muscle / 0.688
3ffk ATPActin, alpha skeletal muscle / 0.687
4iak ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.683
2a41 ATPActin, alpha skeletal muscle / 0.681
5eoy ADPType 4 fimbrial biogenesis protein PilM / 0.677
2q36 ATPActin, alpha skeletal muscle / 0.676
1nmd ATPMajor actin / 0.675
4fu0 ADPD-alanine--D-alanine ligase / 0.674
4ej7 ATPAminoglycoside 3'-phosphotransferase AphA1-IAB / 0.673
1s22 ATPActin, alpha skeletal muscle / 0.672
3u9d ATPActin, alpha skeletal muscle / 0.670
3x2w ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.670
4kqs IPEFarnesyl pyrophosphate synthase 2.5.1.10 0.669
4wb6 ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.669
1yxq ATPActin, alpha skeletal muscle / 0.668
3fjq ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.668
4ci6 ATPActin / 0.668
3x2v ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.667
4oav ACP2-5A-dependent ribonuclease 3.1.26 0.667
1c0f ATPMajor actin / 0.666
2wzb ADPPhosphoglycerate kinase 1 2.7.2.3 0.666
1mwm ADPPlasmid segregation protein ParM / 0.665
2e2q ADPATP-dependent hexokinase / 0.664
2wvj TTPThymidine kinase, cytosolic 2.7.1.21 0.664
4ceg ADPAurora kinase A 2.7.11.1 0.664
1lot ATPActin, alpha skeletal muscle / 0.663
5ce3 ADPProtein kinase YopO / 0.662
4aw1 ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.661
2pup ADPMethylthioribose kinase 2.7.1.100 0.659
3hpr AP5Adenylate kinase / 0.659
3tpt ADPSerine/threonine-protein kinase toxin HipA / 0.659
4a2b AGSCell division protein FtsA / 0.659
4uak ADPSerine/threonine-protein kinase MRCK beta 2.7.11.1 0.659
3wt0 ATPCell division protein FtsA / 0.658
4k41 ATPActin, alpha skeletal muscle / 0.658
1qz5 ATPActin, alpha skeletal muscle / 0.657
3mn6 ATPActin-5C / 0.657
4a2a ATPCell division protein FtsA / 0.656
4m69 ANPReceptor-interacting serine/threonine-protein kinase 3 2.7.11.1 0.656
4oau ADP2-5A-dependent ribonuclease 3.1.26 0.656
1ig1 ANPDeath-associated protein kinase 1 2.7.11.1 0.655
1j7u ANPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.655
1q8y ADPSerine/threonine-protein kinase SKY1 2.7.11.1 0.655
3el2 ATPActin-5C / 0.655
1nm1 ATPMajor actin / 0.654
3chw ATPMajor actin / 0.654
3orl AGSSerine/threonine protein kinase / 0.654
2olc ADPMethylthioribose kinase 2.7.1.100 0.653
1qx4 FADNADH-cytochrome b5 reductase 3 1.6.2.2 0.651
4dqw ATPInosine-5'-monophosphate dehydrogenase / 0.651
1kxp ATPActin, alpha skeletal muscle / 0.650
3w2e NADNADH-cytochrome b5 reductase 3 1.6.2.2 0.650