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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2cf9 348 Prothrombin 3.4.21.5

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2cf9 348Prothrombin 3.4.21.5 1.164
2cf8 ESHProthrombin 3.4.21.5 1.025
1ype UIPProthrombin 3.4.21.5 0.926
2cn0 F25Prothrombin 3.4.21.5 0.917
1ypj UIBProthrombin 3.4.21.5 0.865
1ypg UIRProthrombin 3.4.21.5 0.842
1vzq SHYProthrombin 3.4.21.5 0.838
1oyt FSNProthrombin 3.4.21.5 0.833
2bok 784Coagulation factor X 3.4.21.6 0.784
4ax9 N5NProthrombin 3.4.21.5 0.774
2zfq 45UProthrombin 3.4.21.5 0.760
1ypm RA4Prothrombin 3.4.21.5 0.758
2v3o I26Prothrombin 3.4.21.5 0.758
2zhq 27UProthrombin 3.4.21.5 0.758
4ayy 9MXProthrombin 3.4.21.5 0.755
2znk 31UProthrombin 3.4.21.5 0.754
2zg0 50UProthrombin 3.4.21.5 0.751
4baq M4ZProthrombin 3.4.21.5 0.749
4e7r 0NWProthrombin 3.4.21.5 0.749
4e5i 0N9Polymerase acidic protein / 0.744
1c4v IH2Prothrombin 3.4.21.5 0.739
2zgx 29UProthrombin 3.4.21.5 0.739
4bam MM9Prothrombin 3.4.21.5 0.738
4bao MVFProthrombin 3.4.21.5 0.737
3utu 1TSProthrombin 3.4.21.5 0.736
3biv 11UProthrombin 3.4.21.5 0.735
2zfr 46UProthrombin 3.4.21.5 0.734
4ban M6SProthrombin 3.4.21.5 0.732
1ghv 120Prothrombin 3.4.21.5 0.728
2zda 32UProthrombin 3.4.21.5 0.728
3plp BBACationic trypsin 3.4.21.4 0.725
4bak M67Prothrombin 3.4.21.5 0.725
2ziq 26UProthrombin 3.4.21.5 0.724
2bdy UNBProthrombin 3.4.21.5 0.723
2zhw 12UProthrombin 3.4.21.5 0.723
7kme ACE_0BN_CHG_PRRProthrombin 3.4.21.5 0.721
1f92 UKPUrokinase-type plasminogen activator 3.4.21.73 0.719
2gde SN3Prothrombin 3.4.21.5 0.718
4bah MELProthrombin 3.4.21.5 0.713
3hat GLY_VAL_ARG_RNGProthrombin 3.4.21.5 0.710
1d4p BPPProthrombin 3.4.21.5 0.708
1k22 MELProthrombin 3.4.21.5 0.706
2v3h I25Prothrombin 3.4.21.5 0.706
1o0d 163Prothrombin 3.4.21.5 0.702
5cmx 0G6Prothrombin 3.4.21.5 0.699
1c4u IH1Prothrombin 3.4.21.5 0.695
1kts C24Prothrombin 3.4.21.5 0.692
1lpk CBBCoagulation factor X 3.4.21.6 0.690
1wtg 3BPCoagulation factor VII 3.4.21.21 0.690
3biu 10UProthrombin 3.4.21.5 0.681
1d9i 00PProthrombin 3.4.21.5 0.680
1c1u BAIProthrombin 3.4.21.5 0.678
4fui UI3Urokinase-type plasminogen activator 3.4.21.73 0.678
1c5n ESIProthrombin 3.4.21.5 0.675
1ypl RA8Prothrombin 3.4.21.5 0.672
1wv7 5PICoagulation factor VII 3.4.21.21 0.671
1a4w QWEProthrombin 3.4.21.5 0.669
1ae8 AZLProthrombin 3.4.21.5 0.667
1vja 7INUrokinase-type plasminogen activator 3.4.21.73 0.663
1uvs I11Prothrombin 3.4.21.5 0.662
1ypk CCRProthrombin 3.4.21.5 0.659
1riw OSCProthrombin 3.4.21.5 0.658
2a2x NA9Prothrombin 3.4.21.5 0.654
2zhe 13UProthrombin 3.4.21.5 0.653