sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1zyd | ATP | eIF-2-alpha kinase GCN2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1zyd | ATP | eIF-2-alpha kinase GCN2 | / | 0.987 | |
| 3lct | ADP | ALK tyrosine kinase receptor | 2.7.10.1 | 0.701 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.694 | |
| 3lmg | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.693 | |
| 1zy5 | ANP | eIF-2-alpha kinase GCN2 | / | 0.681 | |
| 2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.675 | |
| 3lij | ANP | Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands | / | 0.674 | |
| 2b51 | UTP | RNA editing complex protein MP57 | / | 0.673 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.669 | |
| 3mfu | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.667 | |
| 1fin | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.664 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.661 | |
| 1wpg | ADP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.660 | |
| 4xhg | ADP | Uncharacterized protein | / | 0.653 | |
| 4dt8 | ADN | APH(2'')-Id | / | 0.650 |