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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1zrb 062 Prothrombin 3.4.21.5

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
1zrb 062Prothrombin 3.4.21.5 0.903
2zc9 22UProthrombin 3.4.21.5 0.833
3dux 64UProthrombin 3.4.21.5 0.833
3dhk 23UProthrombin 3.4.21.5 0.829
2zgb 21UProthrombin 3.4.21.5 0.809
2zfp 19UProthrombin 3.4.21.5 0.808
3eq0 2TSProthrombin 3.4.21.5 0.789
2zf0 51UProthrombin 3.4.21.5 0.781
2zff 53UProthrombin 3.4.21.5 0.778
1ta6 177Prothrombin 3.4.21.5 0.770
2zdv 37UProthrombin 3.4.21.5 0.761
1sl3 170Prothrombin 3.4.21.5 0.757
3f68 91UProthrombin 3.4.21.5 0.747
4e5i 0N9Polymerase acidic protein / 0.744
3qtv 06PProthrombin 3.4.21.5 0.738
2zda 32UProthrombin 3.4.21.5 0.732
2znk 31UProthrombin 3.4.21.5 0.723
1nt1 T76Prothrombin 3.4.21.5 0.721
3utu 1TSProthrombin 3.4.21.5 0.709
3qto 10PProthrombin 3.4.21.5 0.708
1z71 L17Prothrombin 3.4.21.5 0.705
3qwc 98PProthrombin 3.4.21.5 0.701
2zfq 45UProthrombin 3.4.21.5 0.694
1ypl RA8Prothrombin 3.4.21.5 0.692
2zgx 29UProthrombin 3.4.21.5 0.686
2zhq 27UProthrombin 3.4.21.5 0.686
1nm6 L86Prothrombin 3.4.21.5 0.683
3p17 99PProthrombin 3.4.21.5 0.683
4bak M67Prothrombin 3.4.21.5 0.680
2zg0 50UProthrombin 3.4.21.5 0.673
2zfr 46UProthrombin 3.4.21.5 0.670
4bam MM9Prothrombin 3.4.21.5 0.670
2zi2 24UProthrombin 3.4.21.5 0.667
2ziq 26UProthrombin 3.4.21.5 0.664
1xm1 GAHProthrombin 3.4.21.5 0.661
4e5f 0N7Polymerase acidic protein / 0.660
1mu8 CDBProthrombin 3.4.21.5 0.658
4bah MELProthrombin 3.4.21.5 0.658
4ban M6SProthrombin 3.4.21.5 0.657
2jh0 701Prothrombin 3.4.21.5 0.654
2jh6 894Prothrombin 3.4.21.5 0.654
2jh5 895Prothrombin 3.4.21.5 0.652