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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1xva SAM Glycine N-methyltransferase 2.1.1.20

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1xva SAMGlycine N-methyltransferase 2.1.1.20 0.824
1h35 R01Squalene--hopene cyclase 4.2.1.129 0.744
1h36 R88Squalene--hopene cyclase 4.2.1.129 0.744
1p0p BCHCholinesterase 3.1.1.8 0.744
1wrl TFPTroponin C, slow skeletal and cardiac muscles / 0.744
3gww SFXNa(+):neurotransmitter symporter (Snf family) / 0.744
3nc9 TR3Ketohexokinase / 0.744
3cy2 MB9Serine/threonine-protein kinase pim-1 2.7.11.1 0.663
3cxw 7CPSerine/threonine-protein kinase pim-1 2.7.11.1 0.661
4fgj 1PQRibosyldihydronicotinamide dehydrogenase [quinone] / 0.660
4y4j LNREndothiapepsin 3.4.23.22 0.657
4jhz 1KVBeta-glucuronidase 3.2.1.31 0.652