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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1vfr FMN Major NAD(P)H-flavin oxidoreductase 1.6.99

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1vfr FMNMajor NAD(P)H-flavin oxidoreductase 1.6.99 1.316
1kqd FMNOxygen-insensitive NAD(P)H nitroreductase / 1.144
1kqc FMNOxygen-insensitive NAD(P)H nitroreductase / 1.114
1kqb FMNOxygen-insensitive NAD(P)H nitroreductase / 1.095
1icu FMNOxygen-insensitive NAD(P)H nitroreductase / 1.065
3x22 FMNOxygen-insensitive NAD(P)H nitroreductase / 1.060
1nec FMNOxygen-insensitive NAD(P)H nitroreductase 1 1.059
1ylr FMNOxygen-insensitive NAD(P)H nitroreductase / 1.057
1yki FMNOxygen-insensitive NAD(P)H nitroreductase / 1.050
1oon FMNOxygen-insensitive NAD(P)H nitroreductase / 1.044
1oo5 FMNOxygen-insensitive NAD(P)H nitroreductase / 1.037
1ylu FMNOxygen-insensitive NAD(P)H nitroreductase / 1.031
1icv FMNOxygen-insensitive NAD(P)H nitroreductase / 1.028
1ooq FMNOxygen-insensitive NAD(P)H nitroreductase / 0.981
2wzv FMNNitroreductase NfnB / 0.959
2wzw FMNNitroreductase NfnB / 0.955
1ds7 FMNOxygen-insensitive NAD(P)H nitroreductase / 0.938
3x21 FMNOxygen-insensitive NAD(P)H nitroreductase / 0.915
3qdl FMNOxygen-insensitive NADPH nitroreductase / 0.908
3koq FMNPutative nitroreductase / 0.905
3pxv FMNNitroreductase / 0.892
3ge6 FMNNitroreductase / 0.858
3e39 FMNNitroreductase / 0.835
3gag FMNPutative NADH dehydrogenase NAD(P)H nitroreductase / 0.818
3eo8 FMNPutative nitroreductase / 0.807
3gh8 FMNIodotyrosine deiodinase 1 1.21.1.1 0.803
3of4 FMNNitroreductase / 0.790
3gfd FMNIodotyrosine deiodinase 1 1.21.1.1 0.785
2isl FNR5,6-dimethylbenzimidazole synthase 1.13.11.79 0.784
2hay FMNPutative NAD(P)H-flavin oxidoreductase / 0.776
2fre FMNNAD(P)H-flavin oxidoreductase / 0.775
4eo3 FMNBacterioferritin comigratory protein/NADH dehydrogenase / 0.765
4qly FMNEnone reductase CLA-ER / 0.762
3bem FMNPutative NAD(P)H nitroreductase MhqN 1 0.761
3hj9 FMNUncharacterized protein / 0.751
4ttb FMNIodotyrosine deiodinase 1 / 0.736
3to0 FMNIodotyrosine deiodinase 1 1.21.1.1 0.732
4xoo FMNCoenzyme F420:L-glutamate ligase / 0.729
4ttc FMNIodotyrosine deiodinase 1 / 0.724
2ifa FMNUncharacterized protein / 0.716
2isj FMN5,6-dimethylbenzimidazole synthase 1.13.11.79 0.715
4hnb FMNLOV protein / 0.713
2isk FNR5,6-dimethylbenzimidazole synthase 1.13.11.79 0.701
3mdd FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.695
1zpt FAD5,10-methylenetetrahydrofolate reductase 1.5.1.20 0.694
2bkj FMNNADPH-flavin oxidoreductase / 0.690
3clt FADElectron transfer flavoprotein subunit alpha / 0.690
2d29 FADAcyl-CoA dehydrogenase / 0.687
2z1q FADAcyl-CoA dehydrogenase / 0.687
4l82 FMNUncharacterized protein / 0.683
3mkh FADNitroalkane oxidase / 0.681
1t6z RBFRiboflavin biosynthesis protein / 0.680
2a1u FADElectron transfer flavoprotein subunit alpha, mitochondrial / 0.678
3fsu FAD5,10-methylenetetrahydrofolate reductase 1.5.1.20 0.676
1a8p FADFerredoxin--NADP reductase / 0.675
1efv FADElectron transfer flavoprotein subunit alpha, mitochondrial / 0.674
3e4v FMNUncharacterized protein / 0.673
1cc2 FADCholesterol oxidase 1.1.3.6 0.670
3owa FADAcyl-CoA dehydrogenase / 0.670
3b6d FAECholesterol oxidase 1.1.3.6 0.667
5cho FADFlavin reductase / 0.667
3djl FADPutative acyl-CoA dehydrogenase AidB 1.3.99 0.664
4m9a FDAAcyl-CoA dehydrogenase / 0.664
2i51 FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding / 0.663
4kto FADPutative isovaleryl-CoA dehydrogenase protein / 0.661
3p4t FAOPutative acyl-CoA dehydrogenase / 0.660
4rhe FMNFlavin prenyltransferase UbiX / 0.660
1udy FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.659
2wet FADTryptophan 5-halogenase / 0.659
4hms FMNPhenazine biosynthesis protein PhzG 1.4 0.659
2q3o FMN12-oxophytodienoate reductase 3 1.3.1.42 0.658
3vy2 FMNFMN-binding protein / 0.655
4opd FDAConserved Archaeal protein / 0.655
2hsa FMN12-oxophytodienoate reductase 3 1.3.1.42 0.654
3clr FADElectron transfer flavoprotein subunit alpha / 0.654
4h4u FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.654
4opc FDAConserved Archaeal protein / 0.654
4d7e FADPutative lysine-N-oxygenase / 0.653
2ok7 FADFerredoxin--NADP reductase, apicoplast / 0.652
2zaf FADNitroalkane oxidase 1.7.3.1 0.652
3fcj FADNitroalkane oxidase 1.7.3.1 0.652