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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1eyy NAP NADP-dependent fatty aldehyde dehydrogenase 1.2.1.4

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1eyy NAPNADP-dependent fatty aldehyde dehydrogenase 1.2.1.4 1.031
1ez0 NAPNADP-dependent fatty aldehyde dehydrogenase 1.2.1.4 0.985
3rhl NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.755
3rho NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.750
3rhj NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.739
3rhr NDPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.732
4go2 TAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.709
2o2r NDPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.705
2o2q NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.704
3rhq NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.702
4gnz NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.693
2hk9 ATRShikimate dehydrogenase (NADP(+)) / 0.683
2ilu NDPLactaldehyde dehydrogenase 1.2.1.22 0.682
2id2 NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.665
4a5l NDPThioredoxin reductase / 0.662
4nmk NAPAldehyde dehydrogenase / 0.661
2ehq NAP1-pyrroline-5-carboxylate dehydrogenase / 0.660
1e4v AP5Adenylate kinase / 0.655
1nzx NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.651
2xdr NDPNAD/NADP-dependent betaine aldehyde dehydrogenase / 0.651
2wme NAPNAD/NADP-dependent betaine aldehyde dehydrogenase / 0.650