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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1e1x NW1 Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1e1x NW1Cyclin-dependent kinase 2 2.7.11.22 0.811
1e1v CMGCyclin-dependent kinase 2 2.7.11.22 0.721
1h1p CMGCyclin-dependent kinase 2 2.7.11.22 0.663
4fgc PQ0NADPH-dependent 7-cyano-7-deazaguanine reductase 1.7.1.13 0.656
3blq ATPCyclin-dependent kinase 9 2.7.11.22 0.654
3rzp PRFNADPH-dependent 7-cyano-7-deazaguanine reductase / 0.653
3s00 Z60Cyclin-dependent kinase 2 2.7.11.22 0.652