sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5kbw	RBF	Riboflavin transporter RibU

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
5kbw	RBF	Riboflavin transporter RibU	/	1.000
3vyf	VYF	Renin	3.4.23.15	0.455
2ab8	MTP	Adenosine kinase	2.7.1.20	0.454
3ime	BZ2	Pantothenate synthetase	6.3.2.1	0.454
3oqk	S52	Renin	3.4.23.15	0.454
3vyd	VYD	Renin	3.4.23.15	0.451
2iko	7IG	Renin	3.4.23.15	0.450
4anu	EM7	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.449
5c8d	5AD	Probable transcriptional regulator	/	0.447
1vbi	NAD	Malate/L-lactate dehydrogenase family protein	/	0.444
3fwf	CAM	Camphor 5-monooxygenase	1.14.15.1	0.442
2uzt	SS3	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.441
3vet	ADP	nebramycin 5' synthase	6.1.2.2	0.441
4nm9	FAD	Bifunctional protein PutA	/	0.440