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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5jtbZMAAdenosine receptor A2a

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5jtbZMAAdenosine receptor A2a/1.000
5k2dZMAAdenosine receptor A2a/0.662
5k2bZMAAdenosine receptor A2a/0.660
5k2cZMAAdenosine receptor A2a/0.654
5k2aZMAAdenosine receptor A2a/0.641
5uviZMAAdenosine receptor A2a/0.636
5iu86DZAdenosine receptor A2a/0.623
4eiyZMAAdenosine receptor A2a/0.620
5iua6DXAdenosine receptor A2a/0.615
3emlZMAAdenosine receptor A2a/0.613
5iubCLRAdenosine receptor A2a/0.583
5iu4ZMAAdenosine receptor A2a/0.555
2ydvNECAdenosine receptor A2a/0.513
5g53NECAdenosine receptor A2a/0.505
4ug2NGIAdenosine receptor A2a/0.500
2ydoADNAdenosine receptor A2a/0.497
3vg9ZMAAdenosine receptor A2a/0.487
4uhrNGIAdenosine receptor A2a/0.486
3uzcT4EAdenosine receptor A2a/0.467
4iaq2GM5-hydroxytryptamine receptor 1B/0.461
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4r20AERCytochrome P450 family 17 polypeptide 2/0.449
3pwhZMAAdenosine receptor A2a/0.449
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.443
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442