sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5iu8 | 6DZ | Adenosine receptor A2a |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 1.000 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.751 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.671 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.669 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.665 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.646 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.642 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.641 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.636 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.635 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.629 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.579 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.570 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.539 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.531 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.517 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.512 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.494 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.477 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.471 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.470 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.458 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.457 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.457 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.454 | |
| 1osv | CHC | Bile acid receptor | / | 0.448 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.446 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.446 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.445 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.445 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.443 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.443 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.441 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.441 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.441 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.441 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.440 |