sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5h8t | RTL | Retinol-binding protein 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5h8t | RTL | Retinol-binding protein 1 | / | 1.000 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.582 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.580 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.500 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.497 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.476 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.463 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.456 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.454 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.454 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.453 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.452 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.451 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.450 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.450 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.449 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.448 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 1cbs | REA | Cellular retinoic acid-binding protein 2 | / | 0.446 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.446 | |
| 1uom | PTI | Estrogen receptor | / | 0.446 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.446 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.446 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.445 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.444 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.444 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.443 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.443 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.442 | |
| 3up3 | XCA | aceDAF-12 | / | 0.442 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.440 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 |