sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5fm6 | ADP | RuvB-like helicase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5fm6 | ADP | RuvB-like helicase | / | 1.000 | |
| 4ww4 | ADP | RuvB-like helicase | / | 0.551 | |
| 1w5s | ADP | ORC1-type DNA replication protein 2 | / | 0.470 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.466 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.461 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.457 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.451 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.450 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.450 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.445 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 4s1h | ADP | Pyridoxal kinase, putative | / | 0.441 |