sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5f1x	ATP	78 kDa glucose-regulated protein

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
5f1x	ATP	78 kDa glucose-regulated protein	/	1.000
3ldl	ATP	78 kDa glucose-regulated protein	/	0.608
5f2r	ACP	78 kDa glucose-regulated protein	/	0.559
1ngi	ANP	Heat shock cognate 71 kDa protein	/	0.483
1ngh	ATP	Heat shock cognate 71 kDa protein	/	0.479
1atr	ADP	Heat shock cognate 71 kDa protein	/	0.477
1ats	ADP	Heat shock cognate 71 kDa protein	/	0.473
3ldp	3P1	78 kDa glucose-regulated protein	/	0.471
1ngb	ADP	Heat shock cognate 71 kDa protein	/	0.470
3hsc	ADP	Heat shock cognate 71 kDa protein	/	0.467
1nge	ATP	Heat shock cognate 71 kDa protein	/	0.466
1ngc	ADP	Heat shock cognate 71 kDa protein	/	0.459
2qwq	ADP	Heat shock cognate 71 kDa protein	/	0.455
3fe1	ADP	Heat shock 70 kDa protein 6	/	0.450
2qwr	ANP	Heat shock cognate 71 kDa protein	/	0.447