sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5dx1	SFG	Histone-arginine methyltransferase CARM1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
5dx1	SFG	Histone-arginine methyltransferase CARM1	/	1.000
5dx8	SFG	Histone-arginine methyltransferase CARM1	/	0.573
3b3f	SAH	Histone-arginine methyltransferase CARM1	/	0.554
5dxj	SFG	Histone-arginine methyltransferase CARM1	/	0.547
2y1w	SFG	Histone-arginine methyltransferase CARM1	/	0.543
5dxa	SFG	Histone-arginine methyltransferase CARM1	/	0.522
2y1x	SAH	Histone-arginine methyltransferase CARM1	/	0.517
5dwq	SFG	Histone-arginine methyltransferase CARM1	/	0.501
1f3l	SAH	Protein arginine N-methyltransferase 3	/	0.497
2v74	SAH	Histone-arginine methyltransferase CARM1	/	0.484
4c03	SFG	Protein arginine N-methyltransferase 6	/	0.456