sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 1.000 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.463 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.461 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.455 | |
| 3lu8 | IQX | Serum albumin | / | 0.454 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.452 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.452 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 3aba | FLI | Cytochrome P450 | / | 0.448 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.448 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.444 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.442 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.440 |