sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5a4k	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
5a4k	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	1.000
1h66	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.637
1kbo	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.611
5eai	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.601
1gg5	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.594
1qbg	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.590
1dxq	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.584
1d4a	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.576
1dxo	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.576
1kbq	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.576
1h69	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.569