sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4zm6	ACO	N-acetyl-beta-D glucosaminidase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4zm6	ACO	N-acetyl-beta-D glucosaminidase	/	1.000
5kgp	ACO	Predicted acetyltransferase	/	0.506
5kf2	ACO	Predicted acetyltransferase	/	0.483
5kf8	ACO	Predicted acetyltransferase	/	0.481
5kf9	ACO	Predicted acetyltransferase	/	0.480
1b87	ACO	Aac(6')-Ii protein	/	0.475
5kgh	ACO	Predicted acetyltransferase	/	0.475
3tfy	COA	N-alpha-acetyltransferase 50	2.3.1	0.466
2a4n	COA	Aac(6')-Ii protein	/	0.457
3exn	ACO	Probable acetyltransferase	/	0.456
5kf1	ACO	Predicted acetyltransferase	/	0.456
5kgj	ACO	Predicted acetyltransferase	/	0.447