sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4z28 | BTN | Hoefavidin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4z28 | BTN | Hoefavidin | / | 1.000 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.591 | |
| 4bx7 | B4F | Streptavidin | / | 0.520 | |
| 1mk5 | BTN | Streptavidin | / | 0.507 | |
| 1i9h | BNI | Streptavidin | / | 0.506 | |
| 4gda | BTN | Streptavidin | / | 0.503 | |
| 2izf | BTN | Streptavidin | / | 0.498 | |
| 1swt | BTN | Streptavidin | / | 0.496 | |
| 4dne | DTB | Streptavidin | / | 0.496 | |
| 1sre | HAB | Streptavidin | / | 0.495 | |
| 3ry2 | BTN | Streptavidin | / | 0.494 | |
| 1srg | MHB | Streptavidin | / | 0.490 | |
| 2izh | BTN | Streptavidin | / | 0.489 | |
| 1stp | BTN | Streptavidin | / | 0.488 | |
| 1df8 | BTN | Streptavidin | / | 0.487 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.482 | |
| 2rtg | BTN | Streptavidin | / | 0.480 | |
| 2rti | GLL | Streptavidin | / | 0.479 | |
| 2rte | BTN | Streptavidin | / | 0.476 | |
| 2rtd | BTN | Streptavidin | / | 0.475 | |
| 2avi | BTN | Avidin | / | 0.474 | |
| 2izk | GLL | Streptavidin | / | 0.474 | |
| 1srf | MTB | Streptavidin | / | 0.470 | |
| 1sri | DMB | Streptavidin | / | 0.470 | |
| 2izl | IMI | Streptavidin | / | 0.469 | |
| 2rtr | IMI | Streptavidin | / | 0.466 | |
| 3wzn | BTN | Streptavidin | / | 0.466 | |
| 1rxh | BNI | Streptavidin | / | 0.462 | |
| 2uz2 | BTN | Avd protein | / | 0.461 | |
| 2rtf | BTN | Streptavidin | / | 0.460 | |
| 2rtq | IMI | Streptavidin | / | 0.459 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2uyw | BTN | Avd protein | / | 0.458 | |
| 2rtn | IMI | Streptavidin | / | 0.457 | |
| 2rtp | IMI | Streptavidin | / | 0.457 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.456 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.455 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1srj | NAB | Streptavidin | / | 0.454 | |
| 3wyq | BTN | Streptavidin | / | 0.454 | |
| 1luq | BTN | Streptavidin | / | 0.453 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.452 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1srh | MOB | Streptavidin | / | 0.451 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.451 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.449 | |
| 2rtk | GLL | Streptavidin | / | 0.448 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.446 | |
| 2izg | BTN | Streptavidin | / | 0.446 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.446 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 2rto | IMI | Streptavidin | / | 0.443 | |
| 3rdq | DTB | Streptavidin | / | 0.443 | |
| 1lcw | SHM | Streptavidin | / | 0.442 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.442 | |
| 1lcz | BH7 | Streptavidin | / | 0.441 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.441 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1nc9 | IMI | Streptavidin | / | 0.440 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 |