sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4yj2 | GTP | Tubulin alpha-1B chain |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 1.000 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.456 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 5ftf | ADP | TPR domain protein | / | 0.453 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.452 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.445 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.444 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.442 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.442 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.440 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.440 |