sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4wdf	A2P	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4wdf	A2P	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	1.000
2yq9	2AM	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.608
3zbz	OVE	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.572
4wdg	A2P	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.554
2ydd	2AM	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.553
3zbr	NAP	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.520
3zbs	OVE	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.513
2yph	QQY	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.455
2yoz	OVE	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.445
4wda	2AM	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.443
2ydb	NAP	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.441