Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4rwtANPActin-5C

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4rwtANPActin-5C/1.000
4jhdANPActin-5C/0.506
4m63ATPActin-5C/0.493
4pkhADPActin, alpha skeletal muscle/0.469
4k42ADPActin, alpha skeletal muscle/0.448
1c0fATPMajor actin/0.445
3mn9ATPActin-5C/0.442
3u4lATPActin, cytoplasmic 1/0.442