sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4o28	1QS	Nicotinamide phosphoribosyltransferase	2.4.2.12

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4o28	1QS	Nicotinamide phosphoribosyltransferase	2.4.2.12	1.000
4kfp	1R7	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.651
4kfn	1QR	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.627
4kfo	1QS	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.607
4jnm	1LJ	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.603
4lts	LTS	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.588
4jr5	1LS	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.573
4m6p	20R	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.551
4lww	LWW	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.537
4lvb	20N	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.535
4m6q	20T	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.531
2gvj	DGB	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.519
4lva	20M	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.502
4o1d	DGB	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.500