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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ng2OHNTranscriptional activator protein LasR

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4ng2OHNTranscriptional activator protein LasR/1.000
3jpuTY4Transcriptional activator protein LasR/0.539
3ix3OHNTranscriptional activator protein LasR/0.528
3ix4TX1Transcriptional activator protein LasR/0.522
2uv0OHNTranscriptional activator protein LasR/0.515
3ix8TX3Transcriptional activator protein LasR/0.505
3w0gW07Vitamin D3 receptor/0.465
3qm4PN0Cytochrome P450 2D6/0.459
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2a84ATPPantothenate synthetase6.3.2.10.451
1wntNAPL-xylulose reductase1.1.1.100.448
3q43D66M1 family aminopeptidase3.4.110.447
3w0iO11Vitamin D3 receptor/0.445
3vrtYS2Vitamin D3 receptor/0.444
1uydPU8Heat shock protein HSP 90-alpha/0.442
3vt7VDXVitamin D3 receptor/0.442
2aibERGBeta-elicitin cinnamomin/0.441
2y6fM9FIsopenicillin N synthase1.21.3.10.441
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.441
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.440
3w5tLHPVitamin D3 receptor/0.440
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440