sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 1.000 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.648 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.643 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.553 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.548 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.547 | |
| 4wlu | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.534 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.533 | |
| 1sow | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.525 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.515 | |
| 2hjr | APR | Malate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase | / | 0.514 | |
| 1pzf | A3D | Lactate dehydrogenase | / | 0.513 | |
| 1t2d | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.511 | |
| 5mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.501 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.493 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.488 | |
| 4wlv | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.484 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.472 | |
| 4ajo | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.471 | |
| 4wlo | NAI | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.471 | |
| 4ajp | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.470 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.470 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.451 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.447 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 2vhv | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.444 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.443 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.442 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.440 | |
| 4okn | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 |