sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4mq2	2C4	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	2.7.12.1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4mq2	2C4	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	2.7.12.1	1.000
4mq1	2C3	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	2.7.12.1	0.583
2nry	STU	Interleukin-1 receptor-associated kinase 4	2.7.11.1	0.452
3be9	P04	Casein kinase II subunit alpha	2.7.11.1	0.445
2nru	T12	Interleukin-1 receptor-associated kinase 4	2.7.11.1	0.441
2pvn	P63	Casein kinase II subunit alpha	2.7.11.1	0.441
2vag	V25	Dual specificity protein kinase CLK1	2.7.12.1	0.441
3rk7	08Z	Cyclin-dependent kinase 2	2.7.11.22	0.441