sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4mme	29Q	Na(+):neurotransmitter symporter (Snf family)

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4mme	29Q	Na(+):neurotransmitter symporter (Snf family)	/	1.000
4mmd	29E	Na(+):neurotransmitter symporter (Snf family)	/	0.663
4mm9	FVX	Na(+):neurotransmitter symporter (Snf family)	/	0.636
4mmf	29Q	Na(+):neurotransmitter symporter (Snf family)	/	0.630
4mm4	8PR	Na(+):neurotransmitter symporter (Snf family)	/	0.617
4mmc	29J	Na(+):neurotransmitter symporter (Snf family)	/	0.590
4mm7	29J	Na(+):neurotransmitter symporter (Snf family)	/	0.560
4xp1	LDP	Sodium-dependent dopamine transporter	/	0.447