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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/1.000
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.580
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.578
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.578
5koiNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.561
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.530
1vrwNAIEnoyl-ACP reductase/0.511
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.507
4o1mNADEnoyl-acyl carrier reductase/0.496
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.494
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.493
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.484
1v35NAIEnoyl-ACP reductase/0.482
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.478
2nq8ZIDEnoyl-ACP reductase/0.475
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.453
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440