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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4lcnGNGCytidine and deoxycytidylate deaminase zinc-binding region

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4lcnGNGCytidine and deoxycytidylate deaminase zinc-binding region/1.000
4hrqAZGCytidine and deoxycytidylate deaminase zinc-binding region/0.543
1u65CP0Acetylcholinesterase3.1.1.70.464
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.463
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.462
4a862ANMajor pollen allergen Bet v 1-A/0.461
4ey6GNTAcetylcholinesterase3.1.1.70.458
1h22E10Acetylcholinesterase3.1.1.70.457
2pncCLUPrimary amine oxidase, liver isozyme/0.457
1dx6GNTAcetylcholinesterase3.1.1.70.456
1odcA8BAcetylcholinesterase3.1.1.70.454
4a81DXCMajor pollen allergen Bet v 1-A/0.454
4a86H35Major pollen allergen Bet v 1-A/0.449
1zgbA1EAcetylcholinesterase3.1.1.70.448
1qtiGNTAcetylcholinesterase3.1.1.70.447
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.446
4araC56Acetylcholinesterase3.1.1.70.446
1e66HUXAcetylcholinesterase3.1.1.70.445
1eveE20Acetylcholinesterase3.1.1.70.445
1zgcA2EAcetylcholinesterase3.1.1.70.445
4a8v2ANMajor pollen allergen Bet v 1-J/0.445
1gpnHUBAcetylcholinesterase3.1.1.70.442
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
1x1bSAHC-20 methyltransferase/0.441
2zsbADPPantothenate kinase2.7.1.330.441
3zv7NHGAcetylcholinesterase3.1.1.70.440