sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4l8m	F46	Mitogen-activated protein kinase 14

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4l8m	F46	Mitogen-activated protein kinase 14	/	1.000
1wbs	LI2	Mitogen-activated protein kinase 14	/	0.513
1kv1	BMU	Mitogen-activated protein kinase 14	/	0.499
1wbv	LI3	Mitogen-activated protein kinase 14	/	0.498
1wbt	WBT	Mitogen-activated protein kinase 14	/	0.494
3p7b	P7B	Mitogen-activated protein kinase 14	/	0.480
3nnu	EDB	Mitogen-activated protein kinase 14	/	0.457
3o8u	BMU	Mitogen-activated protein kinase 14	/	0.457
3uvr	06F	Mitogen-activated protein kinase 14	/	0.457
3hv5	R24	Mitogen-activated protein kinase 14	/	0.448
3hv6	R39	Mitogen-activated protein kinase 14	/	0.441
3nnx	EDD	Mitogen-activated protein kinase 14	/	0.441