Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4kmzFOLFolate receptor beta

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4kmzFOLFolate receptor beta/1.000
4lrhFOLFolate receptor alpha/0.616
4kn0MTXFolate receptor beta/0.613
4kn104JFolate receptor beta/0.601
4kn2LYAFolate receptor beta/0.570
1ry0PG2Aldo-keto reductase family 1 member C3/0.471
1s36CEIObelin/0.457
3d4sTIMBeta-2 adrenergic receptor/0.450
1ry8RUTAldo-keto reductase family 1 member C3/0.449
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.448
5stdUNNScytalone dehydratase4.2.1.940.448
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.447
2xuhTZ4Acetylcholinesterase3.1.1.70.447
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.447
4bj9UHBTankyrase-22.4.2.300.447
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.444
1gt5BZQOdorant-binding protein/0.442
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.442
4pnmNU1Tankyrase-22.4.2.300.442
2aouCQAHistamine N-methyltransferase2.1.1.80.441
2cekN8TAcetylcholinesterase3.1.1.70.440
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.440