sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4kfo	1QS	Nicotinamide phosphoribosyltransferase	2.4.2.12

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4kfo	1QS	Nicotinamide phosphoribosyltransferase	2.4.2.12	1.000
4lts	LTS	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.805
4kfn	1QR	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.787
4o28	1QS	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.678
4kfp	1R7	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.676
4jnm	1LJ	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.657
4m6p	20R	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.609
4jr5	1LS	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.602
4m6q	20T	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.601
4lww	LWW	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.598
4o1d	DGB	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.588
4lva	20M	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.562
4lvb	20N	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.548
2gvj	DGB	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.534