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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4j75TYMTryptophan--tRNA ligase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4j75TYMTryptophan--tRNA ligase/1.000
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.542
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.538
2qujTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.535
3kt3TYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.516
3kt8LTNTryptophan--tRNA ligase, cytoplasmic6.1.1.20.469
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.465
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.463
1i6kTYMTryptophan--tRNA ligase6.1.1.20.460
1x1cSAHC-20 methyltransferase/0.442
2anb5GPGuanylate kinase2.7.4.80.442
3tr05GPGuanylate kinase/0.441