sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4itf | TFY | Vitamin D3 receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4itf | TFY | Vitamin D3 receptor | / | 1.000 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.675 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.669 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.667 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.666 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.663 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.660 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.659 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.658 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.658 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.658 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.655 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.654 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.653 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.652 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.652 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.648 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.648 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.647 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.647 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.646 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.646 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.645 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.644 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.644 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.640 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.639 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.639 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.638 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.638 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.637 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.637 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.636 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.636 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.635 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.635 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.635 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.634 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.634 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.634 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.631 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.630 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.629 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.626 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.624 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.623 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.618 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.617 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.617 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.616 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.616 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.615 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.614 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.610 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.609 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.608 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.607 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.604 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.603 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.600 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.598 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.596 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.595 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.593 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.585 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.581 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.579 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.576 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.575 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.550 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.492 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.451 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.448 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.447 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 4l8u | 9AZ | Serum albumin | / | 0.445 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.443 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.443 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 |