sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4gr1	FAD	Glutathione reductase, mitochondrial	1.8.1.7

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4gr1	FAD	Glutathione reductase, mitochondrial	1.8.1.7	1.000
1grh	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.849
3grs	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.839
1gre	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.794
1grg	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.770
1gra	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.704
1k4q	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.593
1grb	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.569
1bwc	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.554
1gsn	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.545
3sqp	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.523
3dk9	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.485
3dk8	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.478
3dk4	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.455
3dgz	FAD	Thioredoxin reductase 2, mitochondrial	1.8.1.9	0.441