scPDB - Distribution of Cavity Similarity values of 4gkt entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4gkt	0O1	Queuine tRNA-ribosyltransferase	2.4.2.29

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
4gkt	0O1	Queuine tRNA-ribosyltransferase	2.4.2.29	1.000
4gi4	0EX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.704
3ge7	AFQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.702
4fsa	0V3	Queuine tRNA-ribosyltransferase	2.4.2.29	0.641
4fps	0UX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.639
4gh3	0EV	Queuine tRNA-ribosyltransferase	2.4.2.29	0.623
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.600
1y5v	NE8	Queuine tRNA-ribosyltransferase	2.4.2.29	0.568
1y5w	NEZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.557
4gg9	0WW	Queuine tRNA-ribosyltransferase	2.4.2.29	0.556
1q4w	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.553
3sm0	AEK	Queuine tRNA-ribosyltransferase	2.4.2.29	0.550
1y5x	E89	Queuine tRNA-ribosyltransferase	2.4.2.29	0.523
2pwu	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.522
4fr1	0V2	Queuine tRNA-ribosyltransferase	2.4.2.29	0.521
2pot	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.501
4giy	0WY	Queuine tRNA-ribosyltransferase	2.4.2.29	0.499
2bbf	344	Queuine tRNA-ribosyltransferase	2.4.2.29	0.489
1q66	KMB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.486
2z1x	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.483
1efz	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.481
1k4g	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.476
1p0e	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.474
4n3r	2GU	Tankyrase-1	2.4.2.30	0.471
4q8p	CKR	Queuine tRNA-ribosyltransferase	2.4.2.29	0.471
1q63	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.465
4fgc	PQ0	NADPH-dependent 7-cyano-7-deazaguanine reductase	1.7.1.13	0.465
1it7	GUN	tRNA-guanine(15) transglycosylase	2.4.2.48	0.463
1ozq	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.457
2oal	FAD	Flavin-dependent tryptophan halogenase RebH	1.14.19.9	0.457
3eya	TDP	Pyruvate dehydrogenase [ubiquinone]	1.2.5.1	0.457
4mmf	29Q	Na(+):neurotransmitter symporter (Snf family)	/	0.455
3w0a	DS5	Vitamin D3 receptor	/	0.454
4ia3	BIV	Vitamin D3 receptor A	/	0.452
2azz	TCH	Phospholipase A2, major isoenzyme	3.1.1.4	0.451
3vt7	VDX	Vitamin D3 receptor	/	0.450
4hvx	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.450
1k4h	APQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.449
4ia7	BIV	Vitamin D3 receptor A	/	0.449
3sn7	540	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.448
4c2p	X8Z	Angiotensin-converting enzyme	3.2.1	0.448
4ia1	BIV	Vitamin D3 receptor A	/	0.448
4nc3	ERM	5-hydroxytryptamine receptor 2B	/	0.447
3srs	M23	Dihydrofolate reductase	1.5.1.3	0.446
4h3i	10V	Beta-secretase 1	3.4.23.46	0.446
2zlc	VDX	Vitamin D3 receptor	/	0.445
5a8e	XTK	Beta-1 adrenergic receptor	/	0.445
1ie9	VDX	Vitamin D3 receptor	/	0.444
1db1	VDX	Vitamin D3 receptor	/	0.443
1s19	MC9	Vitamin D3 receptor	/	0.443
2hb7	O1C	Vitamin D3 receptor	/	0.443
2ywv	ADP	Phosphoribosylaminoimidazole-succinocarboxamide synthase	/	0.443
3vt9	YI4	Vitamin D3 receptor	/	0.443
5bp9	SAH	Putative methyltransferase protein	/	0.443
1kij	NOV	DNA gyrase subunit B	/	0.442
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.442
2oci	TYC	Valacyclovir hydrolase	3.1	0.442
3vtc	TK3	Vitamin D3 receptor	/	0.442
4l17	DNQ	Glutamate receptor 2	/	0.442
1ie8	KH1	Vitamin D3 receptor	/	0.441
3a4p	DFQ	Hepatocyte growth factor receptor	2.7.10.1	0.441
3upy	FOM	Oxidoreductase, putative	/	0.441
3zsh	469	Mitogen-activated protein kinase 14	/	0.441
4g31	0WH	Eukaryotic translation initiation factor 2-alpha kinase 3	2.7.11.1	0.441
3h18	PMS	Esterase/lipase	/	0.440