Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4dfrMTXDihydrofolate reductase1.5.1.3

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4dfrMTXDihydrofolate reductase1.5.1.31.000
1dhjMTXDihydrofolate reductase1.5.1.30.802
2drcMTXDihydrofolate reductase1.5.1.30.778
1draMTXDihydrofolate reductase1.5.1.30.737
1dyjDDFDihydrofolate reductase1.5.1.30.701
1jolFFODihydrofolate reductase1.5.1.30.689
1dyhDZFDihydrofolate reductase1.5.1.30.639
1dyiFOLDihydrofolate reductase1.5.1.30.630
1ddrMTXDihydrofolate reductase1.5.1.30.624
1re7FOLDihydrofolate reductase1.5.1.30.567
1ddsMTXDihydrofolate reductase1.5.1.30.553
3och2MXDihydrofolate reductase1.5.1.30.553
3drcMTXDihydrofolate reductase1.5.1.30.550
1rb3MTXDihydrofolate reductase1.5.1.30.545
1rb2FOLDihydrofolate reductase1.5.1.30.526
1drbMTXDihydrofolate reductase1.5.1.30.522
5hi6MTXDihydrofolate reductase/0.519
1tdrMTXDihydrofolate reductase1.5.1.30.490
4x5iFOLDihydrofolate reductase1.5.1.30.476
4x5jFOLDihydrofolate reductase1.5.1.30.476
1dhiMTXDihydrofolate reductase1.5.1.30.471
1rd7FOLDihydrofolate reductase1.5.1.30.460
4cd2FOLDihydrofolate reductase1.5.1.30.458
1ra3MTXDihydrofolate reductase1.5.1.30.456