sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4c9w	VGH	7,8-dihydro-8-oxoguanine triphosphatase	3.6.1.55

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4c9w	VGH	7,8-dihydro-8-oxoguanine triphosphatase	3.6.1.55	1.000
5ans	RX8	7,8-dihydro-8-oxoguanine triphosphatase	3.6.1.55	0.517
1m8h	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.457
2aq8	NAI	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.457
3gwf	NAP	Cyclohexanone monooxygenase	/	0.450
1m8d	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.449
2v58	LZJ	Biotin carboxylase	6.3.4.14	0.448
5cho	FAD	Flavin reductase	/	0.448
1pax	DHQ	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.447
4a81	DXC	Major pollen allergen Bet v 1-A	/	0.446
1m8h	6NI	Nitric oxide synthase, inducible	1.14.13.39	0.444
2y37	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.444
4iar	ERM	5-hydroxytryptamine receptor 1B	/	0.443
4js9	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.443
1lgt	BP3	Biphenyl-2,3-diol 1,2-dioxygenase	1.13.11.39	0.441